- Agent:“Hi Sarah, your annual is due. We have Tuesday 2pm or Thursday 9am open this week.”
- Sarah:“I'd like to come in but I'm slammed until late October.”
- Agent:“No problem. October 24th at 10am or November 6th at 3pm?”
Better care. Better margins. Better mornings.
Patient calls answered around the clock. Triage routed without a clipboard. Referrals chased without a Post-it. Prior authorisations completed before the next appointment.
Karmaflow is an autonomous AI workforce platform for healthcare. Companies use it to deploy AI agents that run the operational layer of your clinic — so your clinical staff can stay where they belong, with patients, not phones.
The 64 hours nobody is at the desk.
From Friday at 5pm to Monday at 9am — sixty-four hours your clinic, your pharmacy, your lab is closed. But your patients aren't. Your payers aren't. Your inventory isn't. Your competitors aren't.
A Karmaflow workforce holds the operation while your team rests. By Monday morning, the inbox is clean, the leads are qualified, the prior auths are resubmitted, and the team starts the week without a backlog.
Three voices, one operating layer
“My front desk drowns in voicemails between 5pm Friday and 9am Monday. We hire to be there for patients, not phones.”
Your institutional brain. On every device. Always on.
Every policy, protocol, vendor, contract, credential, reimbursement rule, and clinical guideline your team needs is one question away — grounded in your actual documents, with provenance attached.
No more “ask Sarah, she'll know.” No more onboarding spreadsheets. No more answers that contradict last quarter's update. The platform reads your handbooks once. After that, your staff just asks.
After-hours suspected sepsis triggers our urgent escalation pathway:
1. On-call physician paged immediately via PagerDuty
2. Patient guided to nearest ER via the WAYP routing tool
3. Intake form auto-completed for ER handoff
4. Family contact attempted via primary contact + emergency
5. Documentation logged to EMR under sepsis triage flag
The supply story your reorder rules can't tell.
Your inventory system reorders. That's a rule. What it can't do is think through your supply situation.
A Karmaflow operations agent reads your inventory the way a senior operations director would: noticing one supplier has shorted three deliveries in a row across two locations; that a slow-moving SKU is quietly draining margin and the vendor still won't take it back; that an upcoming product recall affects four of your stocked items and you'll need substitution guidance ready before patients call. Then it does something about each of them.
- Ondansetron 4mg
- Amoxicillin 500mg
- Metformin 850mg
- Atorvastatin 40mg
- Clopidogrel 75mg
- Hematology tubes EDTA
- Coag tubes citrate
- Urine cups · 90mL
- Reagent X · QBC
- Slide cassette
- Nitrile glove · M
- Surgical mask · L3
- Suture kit · 4-0 vicryl
- Wound dressing · 4x4
- Saline 250mL
Your billing system bills. We surface what your billing system can't see.
Real-time claims to OHIP, RAMQ, MSP, and private payers — that's table stakes. Karmaflow runs the financial intelligence above the billing layer.
A Karmaflow finance agent thinks through your operation the way a part-time CFO would, except continuously. It notices that one service line has quietly become unprofitable since a payer fee schedule change. It reads patient receivables aging not as a list to chase but as a portfolio to triage. When your Aetna contract is up for renewal in 90 days, it has already read every claim, modelled your true margin, and drafted the renegotiation brief.
Integrates with the PMS you already run via : Accuro, OSCAR, TELUS PS Suite, Practice Solutions, Cliniko, Jane, and others.
- Annual physicals46%
- Cosmetic injectables15%
- Chronic care visits52%
- Vaccinations24%
- Aesthetics packages29%
- Specialty consults54%
- Sarah K. · $340 · 94 days2 prior reminders ignored · suggesting payment plan
- Marcus T. · $1,200 · 142 dayspackage treatment unfinished · suggesting completion offer
- Aisha R. · $85 · 67 dayslikely card-on-file failure · retry initiated
The outreach your engagement tool can't have a conversation about.
Recall lists are easy. Tools have generated them for a decade. The problem isn't the list. The problem is what happens when patients reply.
A Karmaflow patient engagement agent has the conversation. It understands when a patient says “I'd like to come in but my schedule is brutal until late October” and proposes specific slots that fit. It reads the response “I switched to a different doctor” and updates the record without escalating it. It notices when a patient who hasn't booked in 18 months suddenly engages and quietly pulls forward their full chart.
- Agent:“Hi Marcus, time for your 6-month follow-up — would Tuesday or Friday work?”
- Marcus:“I switched doctors. Please remove me from your list.”
- Agent:“Hi Aisha, time to schedule your 4-week post-op check. Wednesday 11am or Friday 2pm?”
- Aisha:“Actually I've had some increasing pain in the area, is that normal?”
As many teammates as you need. One workforce. One source of truth.
From first ring to end-of-day digest, every agent runs its own workflow on the same shared model. Add more as your operations grow.
- 01
Intake Agent
- MISSION
- Answers patient calls 24/7. Captures symptoms. Triages urgency.
- CHANNELS
- Voice · SMS · Web chat
- KPIS
- Response time · Capture completeness · Triage accuracy
- 02
Triage & Routing Agent
- MISSION
- Maps symptoms to appropriate care path. Books with the right provider. Handles tertiary insurance routing.
- CHANNELS
- Internal coordination
- KPIS
- Routing accuracy · Time to schedule · Provider load balance
- 03
Care Coordination Agent
- MISSION
- Chases referrals, prior auths, and cross-provider coordination. Handles the documentation back-and-forth.
- CHANNELS
- Voice · Email · Fax · Portal
- KPIS
- Referral completion rate · Auth turnaround · Cross-provider handoff time
- 04
Research Agent
- MISSION
- Pulls literature, guidelines, and KOL context for clinicians on demand. Surfaces evidence at the moment of decision.
- CHANNELS
- Internal
- KPIS
- Time-to-evidence · Citation accuracy · Clinician adoption rate
- 05
Anomaly Agent
- MISSION
- End-of-day review. Surfaces missed follow-ups, lab anomalies, capacity risks.
- CHANNELS
- Internal · Slack / Teams briefings
- KPIS
- Anomaly catch rate · False positive rate · Time-to-flag
- +
Add another teammate
- MISSION
- Define the workflow you want automated. Karmaflow assembles it on the same shared model.
- CHANNELS
- Voice · SMS · Email · Chat · API
- KPIS
- Your KPIs · Your governance · Your timeline
The pattern your clinician would have walked in cold to.
Modern PMS systems summarise a single visit. They don't read the eight conversations before it.
A Karmaflow research agent reads every prior note, message, lab result, and call from the same patient before today's consult begins. Patterns surface in seconds — adherence drift, missed follow-ups, lab trajectories, symptoms reported casually that never got flagged. Your clinician walks into the room with context, not a clipboard.
Reads from Epic, Cerner, athenahealth, NextGen, eClinicalWorks, OSCAR, Accuro, Practice Solutions, and FHIR-native systems via .
- APR 02Annual physicalRoutine. No new findings noted.
- MAY 14Lab · A1C7.2 — early warning
- JUL 21Message · agent triage“feeling tired most days, sleep is fine” — closed without escalation
- AUG 09Refill · metforminAuto-renewed via portal
- AUG 30Follow-up · bookedNo-showed · no reschedule on file
- SEP 04Lab · A1C7.8 — drift continuing
- OCT 18Lab · A1C8.4 — out of range
- NOV 02Call · benefits QAsked about coverage for nutrition counselling
- A1C trending: 7.2 → 7.8 → 8.4 over 5 months. Adherence drift likely.Cross-referenced 3 lab results
- Aug 30 follow-up missed. No reschedule attempted by either side.Scheduling history · 90 days
- Patient mentioned fatigue Jul 21 in a casual message — never escalated.Message archive · semantic match
- Recommend: open today’s consult on adherence, consider nephro pre-screen.Care pathway · type 2 diabetes
The shift change you'll never miss again.
At end of day, the platform reviews everything — every call, every result, every appointment, every referral, every conversation across every channel — and surfaces what needs human attention before tomorrow.
Not a dashboard. A briefing. With the gaps already flagged, the actions already proposed, and the next morning already prepared.
- Patients seen47
- Calls handled134
- Referrals completed12
- Prior auths closed8
- Average response time14 sec
- 3 patients · rising A1C, no follow-up booked
- 1 lab result · outside expected range, unread
- 2 referrals · pending external response > 14 days
- 1 capacity signal · Tuesday next week, 80% over baseline
- →Outreach campaign drafted for the 3 A1C patients
- →Lab result flagged to Dr. M. for review
- →Referral chase scheduled for tomorrow 9am
- →Capacity alert sent to practice manager
Everyone's chief of staff. Nobody's replacement.
One platform. Five teammates. Every person on your staff has a colleague who knows the patient, the policy, the history, and the next step — before they ask.
A chief of staff doesn't replace anyone. They prepare everyone. They know what's happening across the organisation. They draft the response, surface the context, and make every other person on the team faster, more informed, and less reactive.
- Front desk“Drafts every patient response. Books every follow-up.”
- Nurse“Pulls patient history before each room visit.”
- Doctor“Surfaces evidence and prior decisions in seconds.”
- Practice manager“Flags capacity, no-shows, revenue risks daily.”
- Biller“Closes every prior auth loop. Surfaces every margin question.”
Beneath every workflow, a graph that learns.
Every call, message, referral, and outcome enriches the same shared model. When a pattern emerges — three patients with rising A1C and missed follow-ups, a cluster of post-op patients overdue for assessment, a cohort with a rare medication side effect — the platform surfaces it. You decide what to do.
Built on a native graph engine with embedded data science. Centrality, similarity, community detection, path-finding — running continuously beneath every conversation, every action, every workflow on the platform.
HIPAA-governed. Identity-locked. Audit-trailed.
From the front desk to the trial site.
The same Living Intelligence Layer scales from a single clinic to an entire research portfolio. One platform. One graph. One governance model.
Find every patient who matches in minutes, not weeks.
Across providers, channels, conditions, and consent status — the graph runs node similarity, embedding analysis, and consent mapping in one pass.
Match patients to trials they qualify for.
Inform their physicians. Coordinate consent. Track enrolment. Every step under identity lock and audit trail.
Brief every KOL meeting before it happens.
Trial landscape, publication map, prior interactions, congress activity — assembled by an agent, surfaced before your medical science liaison logs in.
Spot adverse events before they become regulatory events.
Graph-based anomaly detection running continuously across real-world data. Signals surface with provenance, ready for safety review.
HIPAA. Identity lock. Audit ledger.
HIPAA & PHI Protection
Per-tenant data isolation. PII redaction in intermediate processing. BAAs available. SOC 2 Type II in progress. HIPAA-aligned audit extensions for healthcare tenants.
Identity Lock
Sensitive actions — prescription changes, PHI release, payment processing — require verified identity at the point of execution, not at session login. No agent acts as you without your verified approval being on file.
Unified Action Ledger
Every agent decision, every action, every read and write — logged, replayable, exportable, defensible in audit. 30-day retention by default, configurable to your retention policy.
Compliance is not a feature. It is the operating temperature of the platform.
Karmaflow is an autonomous AI workforce platform built for healthcare. Practices and health systems use it to deploy AI agents that handle non-clinical operational work end-to-end — patient calls and messages around the clock, intake and triage routing, recall outreach, prior authorisation chasing, referral coordination, internal staff knowledge access, and end-of-day operational review.
The agents reason through unstructured situations — an upset patient calling to cancel, a vendor dispute spanning three deliveries, a longitudinal patient pattern across five visits — work that rules-based tools, existing PMS, and EMR features can't handle. Your clinical staff stays focused on patient care; the platform handles the operational layer that surrounds it.
Karmaflow operates across primary care, specialty care, health systems, pharmacies, labs, imaging centres, home health, and life sciences research organisations.
PMS and EMR platforms automate what's been pre-defined as a rule. They send appointment reminders on a schedule, generate recall lists, post real-time claims to OHIP, RAMQ, MSP, Medicare, Medicaid, and private payers, and trigger reorder POs at min/max thresholds. That's table stakes in 2026.
Karmaflow is the autonomous workforce that operates above and around those rules — handling the cases no rule was written for. Your PMS reorders inventory; a Karmaflow agent notices a vendor has shorted three deliveries this quarter and drafts the supplier dispute. Your EMR generates a recall list; a Karmaflow agent has the actual conversation with the patient who replies “I'd like to come in but I'm slammed until October.”
Karmaflow doesn't replace your existing systems. It reads from them, writes to them, and does the reasoning-based work they were never designed to do.
It depends on the agent and the integration depth, but the first agents go live faster than most healthcare buyers expect.
Same day to under a week — first phase. Patient-facing administrative agents (answering calls, capturing intake, booking, recall outreach across SMS, voice, and email) and staff-facing knowledge agents (your institutional handbook, made askable) can be live within hours to a few days. These are the highest-value, lowest-risk starting points and require no hardware, no IT project, and no waiting on a vendor's API.
One to four weeks — second phase. Deeper operational agents — care coordination, prior authorisation chasing, financial intelligence, longitudinal patient review — typically deploy in two to four weeks once your team has lived with the first phase and decided where to expand.
Four to twelve weeks — selective phase three. Some integrations require last-mile setup: bespoke hardware, on-site managed services, or supervised integration with legacy systems through our Human Interface feature. These require manual approval from Karmaflow's deployment team and are scoped per-practice.
The principle is gradual, deliberate adoption — not a big-bang rollout. Most practices stay on the first phase for weeks before deciding what to add next.
For nearly every healthcare practice, we recommend two starting agents — both low-risk, high-impact, and requiring no integration into your clinical systems on day one:
Patient-facing administrative agent (24/7). Answers inbound calls and messages around the clock. Handles general administrative questions (hours, location, insurance accepted, appointment availability). Books, reschedules, and confirms appointments. Captures intake information. Routes urgent or clinical situations to the right human with full context. This agent alone solves the weekend voicemail backlog problem most practices live with.
Staff knowledge agent. Reads your existing policies, protocols, vendor lists, credentialing requirements, payer rules, and clinical guidelines once. After that, your team asks plain-language questions and gets grounded answers with citations. Stops the “ask Sarah, she'll know” dependency, accelerates new-hire onboarding, and frees senior staff from being unofficial helpdesks.
Most practices run these two agents for two to four weeks before adding more. That deliberate pace builds team trust and gives the platform time to learn your specific patterns before scope expands.
Karmaflow is built on a defence-in-depth security posture purpose-fit for regulated healthcare environments across multiple jurisdictions:
- AES-256 encryption in transit and at rest, per-tenant data isolation, and PII / PHI redaction in intermediate processing.
- United States: HIPAA support with Business Associate Agreements (BAAs) available for healthcare tenants. SOC 2 Type II audit in progress.
- Canada: PIPEDA-aligned data handling for federal jurisdiction; PHIPA-configurable controls for Ontario healthcare deployments; provincial privacy framework support across Alberta (HIA), British Columbia (PIPA), Quebec (Loi 25), and other provinces.
- Identity Lock on sensitive actions. Anything involving PHI release, prescription changes, or payment processing requires verified identity at the point of execution — not just at session login. No agent acts on your authority without your approval being on file.
- Unified audit ledger. Every agent decision, read, and write is logged, replayable, and exportable. Defensible in audit.
- Channel compliance for outbound communications: TCPA (US), CAN-SPAM (US), CASL (Canada), with consent and quiet-hours enforced automatically.
For practices in the UK, Australia, and EU markets, equivalent frameworks (UK GDPR, Australian Privacy Act, EU GDPR) are configurable as tenant policies. If your organisation has specific compliance requirements beyond these baselines — state-level US requirements, organisational controls, payer-specific clauses — they're configurable, not feature requests.
Yes — and this is where Karmaflow does something different from most AI vendors.
Most platforms require an API or formal integration. We support those when they exist. For the systems that don't have APIs, or where the API doesn't expose the workflows we need to operate, our feature lets agents drive the software the way your staff does — opening the application, navigating the menus, entering the information, confirming the action. Same screens, same workflow, no integration build, no IT project, no waiting on a vendor.
Practices use Karmaflow alongside the systems they already run, including:
- United States: Epic, Cerner (Oracle Health), athenahealth, NextGen Healthcare, eClinicalWorks, AdvancedMD, DrChrono, Practice Fusion, Kareo, Allscripts (Veradigm), Greenway, ModMed.
- Canada: OSCAR EMR, Accuro, TELUS PS Suite, Practice Solutions (formerly Wolf), Med Access (TELUS), Healthquest, AvaroEMR, Indivica, MOIS.
- Cross-border and specialty: Cliniko, Jane App, ClinicAid, Tebra, SimplePractice, NueMD, OD Link.
- Pharmacy systems: Kroll, Nexxsys, Fillware, McKesson Pharmacy Systems, PrescribeIT, ProPharm, BestRx.
Some Human Interface deployments — particularly those involving on-premise legacy systems or proprietary hardware — require additional setup and supervised configuration. These require manual approval from Karmaflow's deployment team and are scoped per-practice.
This is the question every healthcare buyer should ask, and the honest answer is: agents are configured to know what they don't know and to stop cleanly when they reach that point.
Every agent operates inside guardrails defined by your practice — what kinds of decisions it can make, what kinds of conversations it can hold, what triggers escalation to a human. When a situation falls outside those guardrails, the agent doesn't guess. It routes to the right person on your team with the full context attached: the conversation history, the relevant patient record, the agent's own reasoning trace, and a recommendation for what action might be appropriate.
In operational terms, your team gets fewer interruptions but better-prepared ones. Instead of picking up a voicemail with no context, your clinical lead receives a brief that says “Patient called at 11pm describing symptoms consistent with possible cardiac event. I declined to provide guidance and routed her to the nearest ER. Her chart is open. Please follow up tomorrow.”
Every escalation, every decision, every action is logged in the audit ledger, replayable end-to-end. If something goes wrong, you can reconstruct exactly what happened and why — defensible in malpractice review, regulatory audit, or internal quality assurance.
Pricing scales with usage — conversation volume, executed actions, model consumption, and the depth of integrations required. Phase-one deployments (patient-facing administrative agent and staff knowledge agent) typically start in a predictable monthly range that's affordable for practices of any size, from a single-physician clinic to a multi-site health system.
Pilots run two to four weeks against success criteria you define together with our team — first-contact resolution rate, after-hours capture rate, recall conversion, prior authorisation cycle time, staff time recovered. The pilot is structured so the value case is proven on your patient data, your call volume, and your operational reality before you commit to a full rollout.
Discovery calls are straightforward. We share specific numbers tied to your practice size and the agents you want to start with. We don't share generic pricing decks because every healthcare deployment looks different.
Find your shape of the operation.
Primary Care
The voicemail box that no longer fills.
Health Systems
Care coordination across every site, every shift.
Pharma & Biotech
Cohort discovery, trial matching, MSL workflows.
Specialty Care
Referral pipelines that close themselves.
Imaging & Diagnostics
Result delivery, follow-up, recall — all governed.
Home Health
Coverage that doesn't depend on a 9-to-5 office.
See it running in your clinic, your hospital, your trial site.
Pilots run in 2–4 weeks against your success criteria. We share a real proposal — not a marketing deck.
PHASE ONE LIVE IN UNDER A WEEK · DEEPER AGENTS IN 2–4 WEEKS
HIPAA · PIPEDA · PHIPA · BAA AVAILABLE · SOC 2 TYPE II IN PROGRESS
